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LMNN
Neurodegeneration blog
Author:
Nathan Riguet
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LMNN
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Neurodegeneration blog
Prof. Hilal A. Lashuel
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Neurodegenerative diseases: From novel tools to disease mechanisms to novel biomarkers and therapies
Protein aggregation: From descriptive to quantitative understanding of protein aggregation and clearance in neurodegenerative diseases.
Post-translational Modifications (PTMs): Deciphering the PTM codes of proteins and uncovering their potential as therapeutic targets and molecular switches for regulating protein functions in health and disease.
Computational modelling within LMNN
Publications
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Lashuel lab channel
International Consortia
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Characterization and Validation of Disease-specific Alpha-synuclein Species in Cerebrospinal Fluid (2014 – Present)
Alpha-Synuclein Assay Standardization LEAPS (linked-efforts to accelerate Parkinson’s solutions)
Oligomeric/pS129 Alpha Synuclein LEAPS and Round Robin (2017)
ABL pathway Biomarkers Consortium- Michael J Fox Foundation (2017 – 2019)
European Consortia/aSynProtec: Alpha-synuclein pathology propagation in Parkinson’s disease and quest for novel protective strategies
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